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OMEROS CORP

OMER · Healthcare · $1.4B mkt cap · FY2025 filings · · No moat ·

Doesn't clear the bar

No moat
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The five investor questions

—

Fewer than two aligned fiscal years of revenue and diluted EPS are available; the filing history does not contain a measurable trend.

100

Median gross margin 98.3% over 5y, very stable.

0

Median ROIC -3731.9%, above the 12% hurdle in 0% of years.

28

Net debt/EBITDA n/ax, interest coverage 0x.

24

Owner earnings changed trend unclear over up to the ten most recent annual observations.

The businessTrend component abstained: Fewer than two aligned fiscal years of revenue and diluted EPS are available; the filing history does not contain a measurable trend. The other four 20% weights were renormalized over the scored 80%.

Price vs. value if growth stopped today

A cautious baseline, not a price target: what the shares may support if normalized owner earnings simply hold steady.

Above value if growth stopped todayBelow value if growth stopped today
No price data
Not reported
Unavailable — insufficient owner-earnings data
Unavailable — insufficient growth-model data
$18.95
No price data

This zero-growth estimate assumes trailing owner earnings persist — unreliable for declining businesses. Flag status unavailable — four adjacent recent FY revenue observations are required.

Among the current top-score group, the median current price is 235% above the zero-growth estimate across 49 of the current top 50 companies by Moat Score with both values.

Score records captured Sep 7, 2026.

Exactly which 50 companies?

FTNT, META, MEDP, IBEX, MSFT, GOOG, LULU, ANF, IDXX, TXRH, FHI, QLYS, FFIV, ADBE, LLY, MANH, VEEV, RMD, GRMN, PCTY, EAT, UI, SSD, MNST, DOCS, LRCX, MCO, CPRT, NTAP, NVDA, CORT, SFM, MPTI, ULTA, SN, ROL, CTAS, PAYC, IRMD, INTU, DECK, MORN, JKHY, TPR, LGCY, DAL, GWW, ISRG, MPWR, LOPE

Missing a usable price or zero-growth estimate: ANF.

Model details under moat-index@3.0.0: zero-growth multiple 11.1×, capped-growth comparison at no more than 18×; 9% discount rate; high-end growth 0% (capped at 4%) using min(5y revenue CAGR, 5y diluted-EPS CAGR), clamped to 0%–4%; maintenance capex uses min(capex, D&A); abstain when D&A is unavailable. This is a disclosed model range, not intrinsic value as fact.

18 years of fundamentals

The business, in plain English

ROIC is not available for the latest filed year, FY2025. Across the full 4-year measurable filed record, median ROIC was −155.6%. Over the v3 recent window (2 measurable filed years), median ROIC was −3731.9%. The Returns on Capital filter above scores it 0/100.

The balance sheet carried $68.4M of total debt in FY2025. Balance-Sheet Safety scores it 28/100.

This breakdown is generated from the filed numbers and sub-scores above — no outside narrative, no estimates. Where a filing doesn’t disclose an input, the sentence that would need it is omitted instead of guessed.

FY2008–FY2025 · 18 fiscal years, normalized from OMER’s SEC filings

Sales, as filed$73.8M FY2020
$0$50M$100M2008201420202025
Revenue kept after cost of goods98.8% FY2020
0%50%100%2008201420202025
Standard ROIC or separately labeled Operating ROIC

Exact FY and FY-1 financing invested-capital inputs are required.. Exact FY and FY-1 Operating Invested Capital inputs are required.

Exact FY and FY-1 financing invested-capital inputs are required.. Exact FY and FY-1 Operating Invested Capital inputs are required.

Cash an owner could take out−$2.5M FY2025
$0$200M2008201420202025

The explained ROIC gaps have filed inputs but no meaningful positive invested-capital denominator. Other gaps mean the item is not in the filings for that year. The series is never interpolated or estimated. The Table view lists every filed value, including operating and net margins, total debt, and share count.

Flagship explainer

How OMEROS CORP makes its money

OMEROS CORP's filing does not supply enough comparable lines for a truthful flow chart — here's what is filed:

Table alternative
Filed lineValue% of revenueSource
−$123MUnavailable
  • 10-K · FY 2025Filing detailsAccession 0001437749-26-010636 · filed Mar 31, 2026
Income before tax−$2.8MUnavailable
  • 10-K · FY 2025Filing detailsAccession 0001437749-26-010636 · filed Mar 31, 2026
Income tax$2MUnavailable
  • 10-K · FY 2025Filing detailsAccession 0001437749-26-010636 · filed Mar 31, 2026
−$3.4MUnavailable
  • 10-K · FY 2025Filing detailsAccession 0001437749-26-010636 · filed Mar 31, 2026
Source:
  • 10-K · FY 2025Filing detailsAccession 0001437749-26-010636 · filed Mar 31, 2026
· event Dec 31, 2025 · retrieved Sep 7, 2026 · annual-row source set

Flagship explainer

What OMEROS CORP owns — and owes

OMEROS CORP's filing tags don't support a full breakdown — here's what is filed:

Table alternative
Filed lineValue% of assetsSource
Total assets$326M100%
  • 10-K · FY 2025Filing detailsAccession 0001437749-26-010636 · filed Mar 31, 2026
Cash and equivalents$9.7M3%
  • 10-K · FY 2025Filing detailsAccession 0001437749-26-010636 · filed Mar 31, 2026
$68.4M21%
  • 10-K · FY 2025Filing detailsAccession 0001437749-26-010636 · filed Mar 31, 2026
Stockholders’ equity−$121M−37%
  • 10-K · FY 2025Filing detailsAccession 0001437749-26-010636 · filed Mar 31, 2026
Source:
  • 10-K · FY 2025Filing detailsAccession 0001437749-26-010636 · filed Mar 31, 2026
· event Dec 31, 2025 · retrieved Sep 7, 2026 · annual-row source set

Flagship explainer

What drives OMEROS CORP’s return on equity?

One or more filed inputs needed for the five-factor decomposition are unavailable.

DuPont source inputs
InputValueFiscal yearSource
Net income−$3.4MFY2025
  • 10-K · FY 2025Filing detailsAccession 0001437749-26-010636 · filed Mar 31, 2026
Income before tax−$2.8MFY2025
  • 10-K · FY 2025Filing detailsAccession 0001437749-26-010636 · filed Mar 31, 2026
Operating income−$123MFY2025
  • 10-K · FY 2025Filing detailsAccession 0001437749-26-010636 · filed Mar 31, 2026
RevenueUnavailableFY2025
  • 10-K · FY 2025Filing detailsAccession 0001437749-26-010636 · filed Mar 31, 2026
Ending assets$326MFY2025
  • 10-K · FY 2025Filing detailsAccession 0001437749-26-010636 · filed Mar 31, 2026
Beginning assets$277MFY2024
  • 10-K · FY 2024Filing detailsAccession 0001437749-26-010636 · filed Mar 31, 2026
Ending equity−$121MFY2025
  • 10-K · FY 2025Filing detailsAccession 0001437749-26-010636 · filed Mar 31, 2026
Beginning equity−$183MFY2024
  • 10-K · FY 2024Filing detailsAccession 0001437749-26-010636 · filed Mar 31, 2026
Source: · event Dec 31, 2025 · retrieved Sep 7, 2026 · annual-row source set

Flagship explainer

Where OMEROS CORP's cash went

OMEROS CORP’s filing does not supply enough provenance-matched cash-flow lines for a truthful flow chart — here’s what is filed:

Table alternative
Filed lineValue% of cash from operationsSource
Cash from operations−$116M−100%
  • 10-K · FY 2025Filing detailsAccession 0001437749-26-010636 · filed Mar 31, 2026
Depreciation and amortization$9640001%
  • 10-K · FY 2025Filing detailsAccession 0001437749-26-010636 · filed Mar 31, 2026
Source:
  • 10-K · FY 2025Filing detailsAccession 0001437749-26-010636 · filed Mar 31, 2026
· event Dec 31, 2025 · retrieved Sep 7, 2026 · annual-row source set

Curated 19-manager tier

Who reported holding OMEROS CORP

Delayed public 13F reports for 2026-Q2—not live positions, trades, or recommendations.

0 holding0 exited0 not holding0/19 resolved19 not retrieved

Named manager positions and quarter-over-quarter changes
ManagerReported positionQuarter-over-quarterFiling accession
Abrams CapitalNot retrievedComparison not retrievedFiling not retrieved
Akre CapitalNot retrievedComparison not retrievedFiling not retrieved
Baupost GroupNot retrievedComparison not retrievedFiling not retrieved
Berkshire HathawayNot retrievedComparison not retrievedFiling not retrieved
Brave Warrior AdvisorsNot retrievedComparison not retrievedFiling not retrieved
Dodge & CoxNot retrievedComparison not retrievedFiling not retrieved
First EagleNot retrievedComparison not retrievedFiling not retrieved
FundsmithNot retrievedComparison not retrievedFiling not retrieved
Gardner Russo & QuinnNot retrievedComparison not retrievedFiling not retrieved
Gates Foundation TrustNot retrievedComparison not retrievedFiling not retrieved
Mairs & PowerNot retrievedComparison not retrievedFiling not retrieved
Markel / Markel-GaynerNot retrievedComparison not retrievedFiling not retrieved
Oakmark / Harris AssociatesNot retrievedComparison not retrievedFiling not retrieved
Pershing SquareNot retrievedComparison not retrievedFiling not retrieved
Polen CapitalNot retrievedComparison not retrievedFiling not retrieved
Sequoia / Ruane CunniffNot retrievedComparison not retrievedFiling not retrieved
Southeastern Asset ManagementNot retrievedComparison not retrievedFiling not retrieved
Tweedy, BrowneNot retrievedComparison not retrievedFiling not retrieved
Yacktman Asset ManagementNot retrievedComparison not retrievedFiling not retrieved

Position size uses shares and filed value from each manager’s 13F. Portfolio weight uses the eligible long-share filing denominator. Changes compare only with the immediately preceding calendar quarter.

Source: Filing source not retrieved · event Jun 30, 2026 · retrieved Sep 7, 2026

Flagship explainer

What OMEROS CORP insiders reported

We could not retrieve insider activity for this rendering; no zero-activity claim is shown.

Unavailable: Form 4 activity could not be retrieved for this rendering.

Moat Score history

17 logged readings since Jul 17, 2026 · append-only, never rewritten

Moat Score over timeLast scored reading of each day, on the 0–100 scale37.9 / 100
0406080100WideNarrowShallowNo moatJul 17, 2026Sep 7, 2026

Breaks in the line mark methodology or normalizer upgrades — readings across versions aren’t compared, so a level shift there isn’t a change in the business.

Tier changesSame-methodology and same-normalizer crossings of the Wide / Narrow / Shallow bars

  1. Normalizer upgraded unstamped (version unknown)moat-xbrl-normalizer@1.1.0 — readings across versions aren’t comparedJul 26, 2026
  2. Methodology upgraded moat-index@2.0.0moat-index@3.0.0 — readings across versions aren’t comparedJul 23, 2026
  3. Methodology upgraded moat-index@1.2.0moat-index@2.0.0 — readings across versions aren’t comparedJul 20, 2026

Scores are logged append-only and never overwritten — this record cannot be reconstructed retroactively, which is exactly why it’s worth keeping.

Insider activity

Form 4 reports mix P/S market or private transactions with compensation-plan mechanics. Activity casually described as “insider selling” can include compensation mechanics; awards, tax withholding, and option exercises are shown by their exact filed class here, never collapsed into “Bought” or “Sold.”

These are disclosed filing facts and arithmetic aggregates, not a signal or verdict.

The insider-filing service is temporarily unavailable, so no partial or guessed answer is shown for OMER.

Track record

How OMEROS CORP’s moat rated in each of the years we can reconstruct from its filings — scored only on what was knowable at the time — and what its price and returns did afterward. The score never saw a price; the two are joined only in hindsight, for education, not as a signal.

Point-in-time scores 2011–2025, one methodology version · reconstructed from filings on file each Dec 31 — never with hindsight

Point-in-time Moat Score (dot colored by tier)Indexed price (total-return (dividends reinvested))Rated Wide-moat that year

How to read this: each dot is what the engine would have scored OMER on that December 31; the line below is its total-return price path (dividends reinvested) in the years since.

0406080100WideNarrowShallowNo moatPoint-in-time Moat Score100200500Indexed price · log scale (2012 = 100)201120142017202020232026

Two tracks, one timeline: the score has its own 0–100 scale (top), the price its own 100-based scale (bottom) — never a shared axis. The price path is a total-return (dividends reinvested) index built from the same data the forward returns use; gaps in the score line are years with no reconstructed rating (see the table for why). The Table view carries every value.

What followed, in the years it rated Wide

In the reconstructed history shown, OMER did not rate Wide-moat in any year, so there is no wide-moat track record to report. That absence is itself the honest answer — we don’t manufacture a comparison where the rating never earned one.

Healthcare context

#402 of 708 scored Healthcare companies, ranked by Moat Score.

Nearest peers by Moat Score

  1. #400CGON CG Oncology, Inc.38.2No moat
  2. #401PYXS Pyxis Oncology, Inc.38.0No moat
  3. #403CELZ Creative Medical Technology Holdings, Inc.37.8No moat
  4. #404BDX BECTON, DICKINSON AND COMPANY37.7No moat

Compare OMER with its nearest peers →All Healthcare companies on the Index →

Common questions about OMER

Does OMEROS CORP have an economic moat?
Based on its FY2025 SEC filings, the Moat Index scores OMEROS CORP (OMER) 37.9 out of 100 — below the Shallow-moat bar, so no moat. The five questions behind that score begin at 20% each; if exactly one genuinely lacks data, the other four weights are renormalized and disclosed. revenue and EPS trend not measurable from the filings, pricing power 100, returns on capital 0, balance-sheet safety 28, capital allocation 24.
How has OMER's Moat Score changed over time?
The record logs 17 readings since Jul 17, 2026; the latest reads 37.9 out of 100 (no moat). No tier changes on record yet. (Methodology or normalizer upgrades on Jul 20, 2026, Jul 23, 2026, Jul 26, 2026 re-based the score; readings across versions aren't compared.) The history is append-only — readings are only ever added, never rewritten.

Scored from primary SEC filings via the public methodology. Educational only — not a recommendation to buy or sell OMER. See the disclaimer.