| MOSLEY WILLIAM DDirector, CEO | Open-market or private sale (S)Table I · Disposed · Ordinary Shares | 30,000 | $922.3484 | $27,670,452 | See lot detail | Oct 1, 2026 | 44 filed lots- Table I · Ordinary Shares: 360 shares at $929.0089 · code S · owned after 372,750.25 ·
- Table I · Ordinary Shares: 855 shares at $930.0334 · code S · owned after 371,895.25 ·
- Table I · Ordinary Shares: 720 shares at $939.2706 · code S · owned after 363,910.25 ·
- Table I · Ordinary Shares: 80 shares at $940.20 · code S · owned after 363,830.25 ·
- Table I · Ordinary Shares: 40 shares at $941.22 · code S · owned after 363,790.25 ·
- Table I · Ordinary Shares: 280 shares at $943.2129 · code S · owned after 363,510.25 ·
- Table I · Ordinary Shares: 440 shares at $944.8064 · code S · owned after 363,070.25 ·
- Table I · Ordinary Shares: 962 shares at $945.9696 · code S · owned after 362,108.25 ·
- Table I · Ordinary Shares: 1,665 shares at $930.994 · code S · owned after 370,230.25 ·
- Table I · Ordinary Shares: 1,320 shares at $932.0368 · code S · owned after 368,910.25 ·
- Table I · Ordinary Shares: 840 shares at $933.2762 · code S · owned after 368,070.25 ·
- Table I · Ordinary Shares: 822 shares at $934.3513 · code S · owned after 367,248.25 ·
- Table I · Ordinary Shares: 640 shares at $935.1494 · code S · owned after 366,608.25 ·
- Table I · Ordinary Shares: 759 shares at $936.4299 · code S · owned after 365,849.25 ·
- Table I · Ordinary Shares: 579 shares at $937.3285 · code S · owned after 365,270.25 ·
- Table I · Ordinary Shares: 640 shares at $938.3194 · code S · owned after 364,630.25 ·
- Table I · Ordinary Shares: 360 shares at $898.0956 · code S · owned after 391,748.25 ·
- Table I · Ordinary Shares: 1,027 shares at $908.5781 · code S · owned after 386,563.25 ·
- Table I · Ordinary Shares: 307 shares at $909.8444 · code S · owned after 386,256.25 ·
- Table I · Ordinary Shares: 840 shares at $910.6933 · code S · owned after 385,416.25 ·
- Table I · Ordinary Shares: 1,146 shares at $912.0438 · code S · owned after 384,270.25 ·
- Table I · Ordinary Shares: 696 shares at $913.0784 · code S · owned after 383,574.25 ·
- Table I · Ordinary Shares: 904 shares at $913.9418 · code S · owned after 382,670.25 ·
- Table I · Ordinary Shares: 960 shares at $915.0083 · code S · owned after 381,710.25 ·
- Table I · Ordinary Shares: 480 shares at $916.0958 · code S · owned after 381,230.25 ·
- Table I · Ordinary Shares: 400 shares at $917.222 · code S · owned after 380,830.25 ·
- Table I · Ordinary Shares: 920 shares at $918.4922 · code S · owned after 379,910.25 ·
- Table I · Ordinary Shares: 517 shares at $900.4618 · code S · owned after 391,231.25 ·
- Table I · Ordinary Shares: 840 shares at $919.5576 · code S · owned after 379,070.25 ·
- Table I · Ordinary Shares: 630 shares at $920.616 · code S · owned after 378,440.25 ·
- Table I · Ordinary Shares: 930 shares at $921.635 · code S · owned after 377,510.25 ·
- Table I · Ordinary Shares: 800 shares at $922.6575 · code S · owned after 376,710.25 ·
- Table I · Ordinary Shares: 760 shares at $923.7821 · code S · owned after 375,950.25 ·
- Table I · Ordinary Shares: 640 shares at $924.7198 · code S · owned after 375,310.25 ·
- Table I · Ordinary Shares: 1,080 shares at $925.8826 · code S · owned after 374,230.25 ·
- Table I · Ordinary Shares: 480 shares at $926.7758 · code S · owned after 373,750.25 ·
- Table I · Ordinary Shares: 640 shares at $927.8963 · code S · owned after 373,110.25 ·
- Table I · Ordinary Shares: 440 shares at $901.4882 · code S · owned after 390,791.25 ·
- Table I · Ordinary Shares: 384 shares at $902.5483 · code S · owned after 390,407.25 ·
- Table I · Ordinary Shares: 696 shares at $903.3632 · code S · owned after 389,711.25 ·
- Table I · Ordinary Shares: 480 shares at $904.3325 · code S · owned after 389,231.25 ·
- Table I · Ordinary Shares: 480 shares at $905.3815 · code S · owned after 388,751.25 ·
- Table I · Ordinary Shares: 601 shares at $906.4232 · code S · owned after 388,150.25 ·
- Table I · Ordinary Shares: 560 shares at $907.4321 · code S · owned after 387,590.25 ·
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| MOSLEY WILLIAM DDirector, CEO | Exercise or conversion of derivative security (M)Table I · Acquired · Ordinary Shares · 1 paired event | 14,000 | $46.23 | $647,220 | 392,108.25 | Oct 1, 2026 | 1 filed lot- Table I · Ordinary Shares: 14,000 shares at $46.23 · code M · owned after 392,108.25 · Paired event: 14,000 NQ Options → 14,000 Ordinary Shares ·
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| MOSLEY WILLIAM DDirector, CEO | Exercise or conversion of derivative security (M)Table II · Disposed · NQ Options · 1 paired event | 14,000 | —Exercise or conversion of derivative security (M) | — | 83,100 | Oct 1, 2026 | 1 filed lot- Table II · NQ Options: 14,000 shares at — (Exercise or conversion of derivative security (M)) · code M · owned after 83,100 · Paired event: 14,000 NQ Options → 14,000 Ordinary Shares ·
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| Morris John ChristopherEVP & CTO | Exercise or conversion of derivative security (M)Table I · Acquired · Ordinary Shares · 1 paired event | 915 | $158.40 | $144,936 | 32,047.25 | Sep 21, 2026 | 1 filed lot- Table I · Ordinary Shares: 915 shares at $158.40 · code M · owned after 32,047.25 · Paired event: 915 NQ Stock Option → 915 Ordinary Shares ·
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| Morris John ChristopherEVP & CTO | Open-market or private sale (S)Table I · Disposed · Ordinary Shares | 9,354 | $877.9079 | $8,211,951 | See lot detail | Sep 21, 2026 | 26 filed lots- Table I · Ordinary Shares: 40 shares at $863.66 · code S · owned after 32,007.25 ·
- Table I · Ordinary Shares: 986 shares at $874.5038 · code S · owned after 27,901.25 ·
- Table I · Ordinary Shares: 974 shares at $875.349 · code S · owned after 26,927.25 ·
- Table I · Ordinary Shares: 760 shares at $876.5447 · code S · owned after 26,167.25 ·
- Table I · Ordinary Shares: 418 shares at $877.364 · code S · owned after 25,749.25 ·
- Table I · Ordinary Shares: 280 shares at $878.3757 · code S · owned after 25,469.25 ·
- Table I · Ordinary Shares: 200 shares at $879.712 · code S · owned after 25,269.25 ·
- Table I · Ordinary Shares: 741 shares at $881.1584 · code S · owned after 24,528.25 ·
- Table I · Ordinary Shares: 200 shares at $881.902 · code S · owned after 24,328.25 ·
- Table I · Ordinary Shares: 320 shares at $883.0775 · code S · owned after 24,008.25 ·
- Table I · Ordinary Shares: 40 shares at $886.27 · code S · owned after 23,968.25 ·
- Table I · Ordinary Shares: 80 shares at $865.11 · code S · owned after 31,927.25 ·
- Table I · Ordinary Shares: 120 shares at $887.9167 · code S · owned after 23,848.25 ·
- Table I · Ordinary Shares: 40 shares at $890.54 · code S · owned after 23,808.25 ·
- Table I · Ordinary Shares: 40 shares at $893.15 · code S · owned after 23,768.25 ·
- Table I · Ordinary Shares: 915 shares at $894.27 · code S · owned after 22,853.25 ·
- Table I · Ordinary Shares: 80 shares at $897.28 · code S · owned after 22,773.25 ·
- Table I · Ordinary Shares: 40 shares at $899.53 · code S · owned after 22,733.25 ·
- Table I · Ordinary Shares: 40 shares at $902.07 · code S · owned after 22,693.25 ·
- Table I · Ordinary Shares: 40 shares at $865.80 · code S · owned after 31,887.25 ·
- Table I · Ordinary Shares: 160 shares at $868.1075 · code S · owned after 31,727.25 ·
- Table I · Ordinary Shares: 80 shares at $869.208 · code S · owned after 31,647.25 ·
- Table I · Ordinary Shares: 200 shares at $870.282 · code S · owned after 31,447.25 ·
- Table I · Ordinary Shares: 520 shares at $871.5615 · code S · owned after 30,927.25 ·
- Table I · Ordinary Shares: 1,000 shares at $872.4244 · code S · owned after 29,927.25 ·
- Table I · Ordinary Shares: 1,040 shares at $873.4914 · code S · owned after 28,887.25 ·
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| Morris John ChristopherEVP & CTO | Exercise or conversion of derivative security (M)Table II · Disposed · NQ Stock Option · 1 paired event | 915 | —Exercise or conversion of derivative security (M) | — | 17,378 | Sep 21, 2026 | 1 filed lot- Table II · NQ Stock Option: 915 shares at — (Exercise or conversion of derivative security (M)) · code M · owned after 17,378 · Paired event: 915 NQ Stock Option → 915 Ordinary Shares ·
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| Romano GianlucaEVP & CFO | Open-market or private sale (S)Table I · Disposed · Ordinary Shares | 49,983.5 | $772.1573 | $38,595,124 | 70,756.5 | Sep 15, 2026 | 1 filed lot- Table I · Ordinary Shares: 49,983.5 shares at $772.1573 · code S · owned after 70,756.5 ·
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| MOSLEY WILLIAM DDirector, CEO | Open-market or private sale (S)Table I · Disposed · Ordinary Shares | 97,889.25 | $772.1432 | $75,584,519 | 378,108.25 | Sep 15, 2026 | 1 filed lot- Table I · Ordinary Shares: 97,889.25 shares at $772.1432 · code S · owned after 378,108.25 ·
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| Teh Ban SengEVP & Chief Commercial Officer | Open-market or private sale (S)Table I · Disposed · Ordinary Shares | 52,730 | $782.0809 | $41,239,128 | See lot detail | Sep 15, 2026 | 24 filed lots- Table I · Ordinary Shares: 914 shares at $771.3753 · code S · owned after 57,626 ·
- Table I · Ordinary Shares: 1,600 shares at $781.348 · code S · owned after 24,920 ·
- Table I · Ordinary Shares: 4,147 shares at $782.5644 · code S · owned after 20,773 ·
- Table I · Ordinary Shares: 1,760 shares at $783.277 · code S · owned after 19,013 ·
- Table I · Ordinary Shares: 1,000 shares at $784.4464 · code S · owned after 18,013 ·
- Table I · Ordinary Shares: 1,040 shares at $786.1423 · code S · owned after 16,973 ·
- Table I · Ordinary Shares: 120 shares at $787.2567 · code S · owned after 16,853 ·
- Table I · Ordinary Shares: 280 shares at $788.43 · code S · owned after 16,573 ·
- Table I · Ordinary Shares: 1,760 shares at $789.8402 · code S · owned after 14,813 ·
- Table I · Ordinary Shares: 560 shares at $791.3643 · code S · owned after 14,253 ·
- Table I · Ordinary Shares: 1,280 shares at $794.7172 · code S · owned after 12,973 ·
- Table I · Ordinary Shares: 3,451 shares at $772.6537 · code S · owned after 54,175 ·
- Table I · Ordinary Shares: 2,166 shares at $795.9457 · code S · owned after 10,807 ·
- Table I · Ordinary Shares: 1,587 shares at $796.8955 · code S · owned after 9,220 ·
- Table I · Ordinary Shares: 530 shares at $797.9715 · code S · owned after 8,690 ·
- Table I · Ordinary Shares: 400 shares at $799.027 · code S · owned after 8,290 ·
- Table I · Ordinary Shares: 2,480 shares at $800.47 · code S · owned after 5,810 ·
- Table I · Ordinary Shares: 1,717 shares at $774.0138 · code S · owned after 52,458 ·
- Table I · Ordinary Shares: 2,315 shares at $775.0148 · code S · owned after 50,143 ·
- Table I · Ordinary Shares: 3,242 shares at $776.1967 · code S · owned after 46,901 ·
- Table I · Ordinary Shares: 3,987 shares at $777.2171 · code S · owned after 42,914 ·
- Table I · Ordinary Shares: 7,259 shares at $778.3464 · code S · owned after 35,655 ·
- Table I · Ordinary Shares: 6,682 shares at $779.2653 · code S · owned after 28,973 ·
- Table I · Ordinary Shares: 2,453 shares at $780.2946 · code S · owned after 26,520 ·
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