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Flagship explainer

What drives BIOCRYST PHARMACEUTICALS, INC.’s return on equity?

ROE is five filed business factors multiplied together.

DuPont return on equity factor treeReturn on equity branches into tax burden, interest burden, operating margin, asset turnover, and the equity multiplier.Return on equity−89%Tax burden99%net income ÷ pretax incomeInterest burden78%pretax ÷ operating incomeOperating margin39%operating income ÷ revenueAsset turnover1.74×revenue ÷ average assetsEquity multiplier-1.69×average assets ÷ average equityAs of 2025-12-31 · 1 SEC filing sourceBuy Like Buffett · buylikebuffett.com
DuPont source inputs
InputValueFiscal yearSource
$264MFY2025
  • 10-K · FY 2025Filing detailsAccession 0001628280-26-012240 · filed Feb 26, 2026
Income before tax$267MFY2025
  • 10-K · FY 2025Filing detailsAccession 0001628280-26-012240 · filed Feb 26, 2026
Operating income$341MFY2025
  • 10-K · FY 2025Filing detailsAccession 0001628280-26-012240 · filed Feb 26, 2026
$875MFY2025
  • 10-K · FY 2025Filing detailsAccession 0001628280-26-012240 · filed Feb 26, 2026
Ending assets$514MFY2025
  • 10-K · FY 2025Filing detailsAccession 0001628280-26-012240 · filed Feb 26, 2026
Beginning assets$490MFY2024
  • 10-K · FY 2024Filing detailsAccession 0001628280-26-012240 · filed Feb 26, 2026
−$119MFY2025
  • 10-K · FY 2025Filing detailsAccession 0001628280-26-012240 · filed Feb 26, 2026
−$476MFY2024
  • 10-K · FY 2024Filing detailsAccession 0001628280-26-012240 · filed Feb 26, 2026
Source: · event Dec 31, 2025 · retrieved Oct 17, 2026 · annual-row source set
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BCRX dupont explainer — Buy Like Buffett · Buy Like Buffett