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How CASTLE BIOSCIENCES, INC. makes its money

Start with a dollar of revenue and follow what the filing says remains.

revenueBranching filed flows with values and percentages directly labeled. Missing filing concepts are omitted rather than estimated.Revenue$344M · 100%Cost of revenue$71M · 21%Gross profit$273M · 79%Operating income−$42.8M · −12%Income before tax−$29.5M · −9%Income tax−$5.4M · −2%Net income−$24.2M · −7%As of 2025-12-31 · 1 SEC filing sourceBuy Like Buffett · buylikebuffett.com

Honest partial: the filing did not provide a normalized tag for Research and development, Selling, general and administrative; those components are omitted, not plugged.

Table alternative
Filed lineValue% of revenueSource
$344M100%
  • 10-K · FY 2025Filing detailsAccession 0001628280-26-012272 · filed Feb 26, 2026
Cost of revenue$71M21%
  • 10-K · FY 2025Filing detailsAccession 0001628280-26-012272 · filed Feb 26, 2026
$273M79%
  • 10-K · FY 2025Filing detailsAccession 0001628280-26-012272 · filed Feb 26, 2026
−$42.8M−12%
  • 10-K · FY 2025Filing detailsAccession 0001628280-26-012272 · filed Feb 26, 2026
Income before tax−$29.5M−9%
  • 10-K · FY 2025Filing detailsAccession 0001628280-26-012272 · filed Feb 26, 2026
Income tax−$5.4M−2%
  • 10-K · FY 2025Filing detailsAccession 0001628280-26-012272 · filed Feb 26, 2026
−$24.2M−7%
  • 10-K · FY 2025Filing detailsAccession 0001628280-26-012272 · filed Feb 26, 2026
Source:
  • 10-K · FY 2025Filing detailsAccession 0001628280-26-012272 · filed Feb 26, 2026
· event Dec 31, 2025 · retrieved Oct 16, 2026 · annual-row source set
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